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The test was first introduced in 1956, using iodine-131 diodrast. [25] [26] Later developments included iodine-131, and then iodine-123, labelled ortho-Iodohippuric acid (OIH, marketed as Hippuran). [27] [28] 99m Tc-MAG3 has replaced 131 I-OIH because of better quality imaging regardless of the level of kidney function, [29] and lower radiation ...
The RAIU test is a reliable measurement when using a dedicated probe with a reproducibility of 1 percent and a 95%-least-significant-change of 3 percent. [3] The normal uptake is between 15 and 25 percent, but this may be forced down if, in the meantime, the patient has eaten foods high in iodine, such as dairy products and seafood. [4]
In one study, researchers gave pregnant women between 100 and 200 microcuries (3.7 and 7.4 MBq) of iodine-131, and later performed abortions to study the women's embryos in an attempt to discover at what stage, and to what extent, radioactive iodine crosses the placental barrier. [67]
Hypothyroidism is common in pregnancy with an estimated prevalence of 2-3% and 0.3-0.5% for subclinical and overt hypothyroidism respectively. [8] Endemic iodine deficiency accounts for most hypothyroidism in pregnant women worldwide while chronic autoimmune thyroiditis is the most common cause of hypothyroidism in iodine sufficient parts of the world.
The absolute indications are a large goiter (especially when compressing the trachea), suspicious nodules or suspected cancer (to pathologically examine the thyroid), and people with ophthalmopathy and additionally if it is the person's preferred method of treatment or if refusing to undergo radioactive iodine treatment. Pregnancy is advised to ...
A ballot initiative in Missouri appears to be picking up steam after clearing a key hurdle last week: a court challenge to its constitutionality, which argued that the language of the submitted ...
enlisting doctors to administer radioactive iron to impoverished pregnant women [5] exposing U.S. soldiers and prisoners to high levels of radiation [4] irradiating the testicles of prisoners, which caused severe birth defects [4] exhuming bodies from graveyards to test them for radiation (without the consent of the families of the deceased) [6]
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