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Nitrofurantoin, trimethoprim-sulfamethoxazole (TMP/SMX), fosfomycin, and pivmecillinam are currently the first-line agents for empiric therapy of simple cystitis. [4] On the other hand, the choice of empiric antimicrobial therapy for pyelonephritis depends on the severity of illness, specific host factors, and the presence of resistant bacteria.
Nitrofurantoin is pregnancy category A in Australia. [3] It is one of the few drugs commonly used in pregnancy to treat UTIs. [38] There is a potential risk of hemolytic anemia in the newborn when used near time of delivery. [3] Newborns of women given this drug late in pregnancy had a higher risk of developing neonatal jaundice. [39]
Pyelonephritis occurs between 20 and 30 times less frequently. [4] They are the most common cause of hospital-acquired infections accounting for approximately 40%. [115] Rates of asymptomatic bacteria in the urine increase with age from two to seven percent in women of child-bearing age to as high as 50% in elderly women in care homes. [42]
Pyelonephritis affects about 1 to 2 per 1,000 women each year and just under 0.5 per 1,000 males. [5] [7] Young adult females are most often affected, followed by the very young and old. [2] With treatment, outcomes are generally good in young adults.
Up to 10% of women have a urinary tract infection in a given year and half of all women have at least one infection at some point in their lives. [ 6 ] [ 7 ] There is an increased risk of asymptomatic or symptomatic bacteriuria in pregnancy due to physiological changes that occur in a pregnant woman which promotes unwanted pathogen growth in ...
Two Indiana parents are in custody after allegedly leaving their 2-year-old daughter in a closet overnight with a space heater turned all the way up.
"In reality," he said, "foodborne illnesses can lead to severe and long-lasting health issues, hospitalization or even death, especially for vulnerable populations like the immunocompromised ...
Nephritis represents the ninth-most-common cause of death among all women in the US (and the fifth leading cause among non-Hispanic black women). [ 19 ] Worldwide, the highest rates [ clarification needed ] of nephritis are 50–55% for African or Asian descent followed by Hispanic at 43% and Caucasian at 17%.
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