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Various neutraceuticals (supplements) are available for equine joint health. Although these products are evaluated for safety, they are not required to prove efficacy, and actual scientific support of their benefits for osteoarthritis in horses are poor. [19]
PSGAG is mostly used in dogs and horses for treating traumatic arthritis and degenerative joint disease (osteoarthritis). [7] It has shown to be better at treating acute than chronic arthritis, though some studies say that its effectiveness in acute cases is still limited if degenerative enzymes have not played a role. [8]
Cosequin is a nutritional supplement for animals. [1] It claims to support joints in pets. [2] Cosequin is manufactured in the by Nutramax Laboratories Veterinary Sciences, Inc. It contains TRH122(R) chondroitin sulfate, FCHG49(R) glucosamine, and manganese ascorbate. Cosequin comes in formulas specific for cats, dogs and horses. [2]
A significant amount of research has been performed on glycosaminoglycans, especially glucosamine and chondroitin, for the treatment of arthritis.These compounds are commonly marketed as nutritional supplements and numerous 'soft therapeutic claims' are made about their health benefits - especially in aging populations. [1]
Hyaluronan is used in treatment of articular disorders in horses, in particular those in competition or heavy work. [66] It is indicated for carpal and fetlock joint dysfunctions, but not when joint sepsis or fracture are suspected. It is especially used for synovitis associated with equine osteoarthritis. It can be injected directly into an ...
Chemical structure of one unit in a chondroitin sulfate chain. Chondroitin-4-sulfate: R 1 = H; R 2 = SO 3 H; R 3 = H. Chondroitin-6-sulfate: R 1 = SO 3 H; R 2, R 3 = H.. Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) [1] composed of a chain of alternating sugars (N-acetylgalactosamine and glucuronic acid).
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