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2. Sacubitril/valsartan - Wikipedia

   en.wikipedia.org/wiki/Sacubitril/valsartan

   [10] [11] [18] To investigate its use for heart failure in those with a preserved LVEF (HFpEF), Novartis funded the PARAGON-HF trial which was designed to investigate the use of sacubitril/valsartan in the treatment of HFpEF patients with a LVEF of 45% or more. Concluding in 2019, it failed to show significance for reducing hospitalisation ...

3. Antihypertensive - Wikipedia

   en.wikipedia.org/wiki/Antihypertensive

   Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34% and of ischaemic heart disease by 21%, and can reduce the likelihood of dementia ...

4. Management of heart failure - Wikipedia

   en.wikipedia.org/wiki/Management_of_heart_failure

   People with heart failure, also known as congestive heart failure (CHF), are educated to undertake various non-pharmacological measures to improve symptoms and prognosis. Such measures include: [2] Moderate physical activity, when symptoms are mild or moderate; or bed rest when symptoms are severe. In individuals with heart failure, increasing ...

5. Valsartan - Wikipedia

   en.wikipedia.org/wiki/Valsartan

   Valsartan, sold under the brand name Diovan among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. [8] It belongs to a class of medications referred to as angiotensin II receptor blockers (ARBs). It is a reasonable initial treatment for high blood pressure. [8] It is taken by mouth. [8]

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7. Angiotensin II receptor blocker - Wikipedia

   en.wikipedia.org/wiki/Angiotensin_II_receptor...

   [7] Candesartan is used experimentally in preventive treatment of migraine. [8] [9] Lisinopril has been found less often effective than candesartan at preventing migraine. [10] The angiotensin II receptor blockers have differing potencies in relation to blood pressure control, with statistically differing effects at the maximal doses. [11]