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This is an accepted version of this page This is the latest accepted revision, reviewed on 7 January 2025. Circumstances, mechanisms, and factors of tobacco consumption on human health "Health effects of smoking" and "Dangers of smoking" redirect here. For cannabis, see Effects of cannabis. For smoking crack cocaine, see Crack cocaine § Health issues. "Smoking and health" redirects here. For ...
The morbidity of cigarette smoking is nearly 50% with 7 million first-hand smokers and 1.2 millions second hand smokers killed each year. [8] Regardless of active or passive smokers, macrophage accumulation is found in the lungs.
Second-hand smoking (SHS) is a combination of sidestream smoke (i.e., smoke emitted from the burning cigarette, pipe, or cigar) and the mainstream smoke exhaled from the lungs of smokers. It contains more than 4,000 chemicals, many of which are known to affect health.
[2] [10] Primary cilia on pancreatic beta cells regulate their function and energy metabolism. Cilia deletion can lead to islet dysfunction and type 2 diabetes. [32] Cilia are assembled during the G 1 phase and are disassembled before mitosis occurs. [33] [11] Disassembly of cilia requires the action of aurora kinase A. [34]
The hyperplasia of airway basal cells is the earliest indication of smoking-related abnormality in the lung. [4] [1] This is followed by shortened cilia, loss of ciliated cells, mucous cell hyperplasia, and loss of cell junctions giving a leaky epithelial barrier. With persistent stress from smoking, the basal cells become disarranged and lose ...
While the study is admittedly crude in nature -- it relies on averages, assumes that the health effects of smoking are evenly spread throughout a smoker's lifetime, presumes that the number of ...
Tobacco smoke, besides being an irritant and significant indoor air pollutant, is known to cause lung cancer, heart disease, chronic obstructive pulmonary disease (COPD), emphysema, and other serious diseases in smokers (and in non-smokers as well). The actual mechanisms by which smoking can cause so many diseases remain largely unknown.
Mucociliary clearance (MCC), mucociliary transport, or the mucociliary escalator describes the self-clearing mechanism of the airways in the respiratory system. [1] It is one of the two protective processes for the lungs in removing inhaled particles including pathogens before they can reach the delicate tissue of the lungs.