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Zinc pyrithione (or pyrithione zinc) is a coordination complex of zinc. It has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis [ 2 ] and dandruff .
Pyrithione is the common name of an organosulfur compound with molecular formula C 5 H 5 NOS, chosen as an abbreviation of pyridinethione, and found in the Persian shallot. [4] It exists as a pair of tautomers, the major form being the thione 1-hydroxy-2(1H)-pyridinethione and the minor form being the thiol 2-mercaptopyridine N-oxide; it crystallises in the thione form. [5]
Like selenium sulfide, zinc pyrithione (a zinc complex with two chelating pyrithione anions) also reduces epidermal turnover and inhibits fungal growth. [3] [unreliable medical source?] It is often administered with ketoconazole for better results. The symptoms do not resolve completely even after prolonged medication.
That means, “Whether it’s safe to take zinc every day as a supplement depends on how much zinc is in the supplement and how much you get from your diet,” says Haggans.
Zinc-rich foods include beef, poultry, pumpkin seeds, fortified breakfast cereals, and seafood (in fact, oysters contain more zinc than any other food). Because zinc is found in so many foods ...
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Structure of zinc pyrithione, a popular antidandruff medicine. Zinc pyrithione is a coordination complex of a sulfur-substituted pyridine-N-oxide. This zinc complex has useful fungistatic and bacteriostatic properties.. [5]
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