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A population of women who were at least 21 years old, of Pima Indian heritage and living near Phoenix, Arizona, was tested for diabetes mellitus according to World Health Organization criteria. The data were collected by the US National Institute of Diabetes and Digestive and Kidney Diseases. We used the 532 complete records. [2] [3]
The overall prevalence increases with age, with the largest increase in people over 65 years of age. [3] The prevalence of diabetes in America is estimated to increase to 48.3 million by 2050. [3] Diabetes mellitus occurs throughout the world, but is more common (especially type 2) in the more developed countries.
Due to the large effect of prevalence upon predictive values, a standardized approach has been proposed, where the PPV is normalized to a prevalence of 50%. [11] PPV is directly proportional [dubious – discuss] to the prevalence of the disease or condition. In the above example, if the group of people tested had included a higher proportion ...
This formula can be calculated algebraically by combining the steps in the preceding description. In fact, post-test probability , as estimated from the likelihood ratio and pre-test probability , is generally more accurate than if estimated from the positive predictive value of the test, if the tested individual has a different pre-test ...
Type 2 diabetes is a progressive condition in which the body becomes resistant to the normal effects of insulin and/or gradually loses the capacity to produce enough insulin in the pancreas. [2] Pre-diabetes means that the blood sugar level is higher than normal but not yet high enough to be type 2 diabetes. [3]
Diabetic nephropathy is responsible for about a third of cases of ESRD worldwide, and an even larger fraction in the developed countries. [53] Worldwide, the prevalence of diabetes is projected to increase from 382 million in 2013, to over 592 million by 2035. This increase is projected to be sharpest in developed countries.
Thus a lowering of disposition index predicts the conversion of insulin resistance to diabetes mellitus type 2. [13] Disposition index, but not insulin resistance, can predict type 2 diabetes in persons with normal blood glucose levels, but who do not have a family history (genetic predisposition) to type 2 diabetes. [14]
In 2012, diabetes caused 356,586 deaths in this region, a zone with the highest prevalence of diabetes in adults (11%) in the world. [16] Turkey reported a prevalence of 33.9% for metabolic syndrome (MS), with a higher prevalence in women (39.6%) than in men (28%). [17]
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