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In September 2024, it was approved for medical use in the United States. [ 1 ] [ 2 ] It is the first antipsychotic drug approved by the US Food and Drug Administration (FDA) to treat schizophrenia that targets cholinergic receptors as opposed to dopamine receptors , which has long been the standard of care.
Antipsychotics by class Generic name Brand names Chemical class ATC code Typical antipsychotics; Acepromazine: Atravet, Acezine: phenothiazine: N05AA04
Antipsychotics can cause weight gain, drowsiness, metabolic syndrome, which can increase risk of heart attack or stroke, or involuntary movements such as blinking or sticking out your tongue.
Saphris – atypical antipsychotic used to treat schizophrenia and bipolar disorder; Serax – anti-anxiety medication of the benzodiazepine class, often used to help during detoxification from alcohol or other addictive substances; Serentil (mesoridazine) – an antipsychotic drug used in the treatment of schizophrenia [1]
Unlike other antipsychotics, pimavanserin is not a dopamine receptor antagonist, [5] but rather is a selective antagonist or inverse agonist of the serotonin 5-HT 2A receptor and to a lesser extent of the serotonin 5-HT 2C receptor. [3] Pimavanserin was first approved for medical use in 2016. [3] It was approved as a generic medication in 2024. [6]
Cenobamate was approved for medical use in the United States in November 2019, [3] [7] [8] [9] and placed in Schedule V of the Controlled Substances Act in March 2020. [10] Cenobamate was approved for medical use in the European Union in March 2021, [5] approved for use in the UK in December 2021, [11] and approved for use in Canada in June ...
Ulotaront (INN Tooltip International Nonproprietary Name; [1] developmental codes SEP-363856, SEP-856) is an investigational antipsychotic that is undergoing clinical trials for the treatment of schizophrenia and Parkinson's disease psychosis.
When these negotiations kick in in 2026, those people are expected to save the most — between 66% and 79% of their prescription cost, as each drug will go from more than $500 per month to less ...