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Skin care cosmetics at a pharmacy. Skin care or skincare is a range of practices that support skin integrity, enhance its appearance, and relieve skin conditions. They can include nutrition, avoidance of excessive sun exposure, and appropriate use of emollients.
Collagen is a structural protein, often referred to as "the steel of biological materials". [14] There are multiple types of collagen: Type I (comprising skin, tendons and ligaments, vasculature and organs, as well as teeth and bone and artery walls); Type II (a component in cartilage); Type III (often found in reticular fibers); and others
Collagen binding is primarily provided by integrins α1β1, α2β1, α10β1 and α11β1. Integrin α1β1 binds to collagen via the MIDAS motif in the α subunit I domain. It preferentially binds collagens IV, VI and type XIII collagen, but also fibril-forming collagens. Specific binding sites in collagen I and IV have been identified.
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