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A representation by Robert Seymour of the cholera epidemic depicts the spread of the disease in the form of poisonous air.. The miasma theory was the predominant theory of disease transmission before the germ theory took hold towards the end of the 19th century; it is no longer accepted as a correct explanation for disease by the scientific community.
Epidemics of the 19th century were faced without the medical advances that made 20th-century epidemics much rarer and less lethal. Micro-organisms (viruses and bacteria) had been discovered in the 18th century, but it was not until the late 19th century that the experiments of Lazzaro Spallanzani and Louis Pasteur disproved spontaneous generation conclusively, allowing germ theory and Robert ...
This began the path to germ specificity within the theory. [49] Louis Pasteur's contemporary Robert Koch devoted much of his scientific study to discovering certain pathogens and connecting them to specific diseases. These scientists were often in competition with one another and so the Koch-Pasteur rivalry is a well-known part of germ theory's ...
The French Louis Pasteur (1822–1895) and German Robert Koch (1843–1910) are the two greatest figures in medical microbiology and in establishing acceptance of the germ theory of disease (germ theory). [1] In 1882, fueled by national rivalry and a language barrier, the tension between Pasteur and the younger Koch erupted into an acute ...
In contrast, the germ theory held that the principal cause of cholera was a germ cell that had not yet been identified. Snow theorised that this unknown germ was transmitted from person to person by individuals ingesting water. John Simon, a pathologist and the lead medical officer for London, labelled Snow's germ theory as "peculiar". [6]
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At the time the "germ theory" of disease had not yet obtained general acceptance, and Koch's announcement was received with considerable skepticism, particularly after it was found that similar "comma bacilli" could be found at times in the feces of persons not suffering from cholera, and often in all sorts of other environments - well and ...
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