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The blood reaching the extremities is not oxygen-rich and when viewed through the skin a combination of factors can lead to the appearance of a blue color. All factors contributing to central cyanosis can also cause peripheral symptoms to appear, but peripheral cyanosis can be observed in the absence of heart or lung failures. [5]
The very term "acrocyanosis" is often applied inappropriately in cases when blue discoloration of the hands, feet, or parts of the face is noted. [1] The principal (primary) form of acrocyanosis is that of a benign cosmetic condition, [ 2 ] sometimes caused by a relatively benign neurohormonal disorder. [ 3 ]
The nail deformity often occurs in people suffering from heart and lung diseases that reduce the amount of oxygen in the blood. It can be a warning sign of a serious problem, doctors say.
The exact cause for sporadic clubbing is unknown. Theories as to its cause include: Vasodilation (i.e., distended blood vessels). [citation needed] Secretion of growth factors (e.g., platelet-derived growth factor and hepatocyte growth factor) from the lungs. [citation needed] Overproduction of prostaglandin E2 by other tissues. [14]
Nail clubbing - nails that curve down around the fingertips with nailbeds that bulge is associated with oxygen deprivation and lung, heart, or liver disease. Koilonychia - spooning, or nails that grow upwards. Associated with iron-deficiency anaemia or vitamin B 12 deficiency. [citation needed] Pitting of the nails is associated with psoriasis.
Very large AVMs cause a marked inability to absorb oxygen, which may be noted by cyanosis (bluish discoloration of the lips and skin), clubbing of the fingernails (often encountered in chronically low oxygen levels), and a humming noise over the affected part of the lung detectable by stethoscope. [4] [5]
Blue baby syndrome can refer to conditions that cause cyanosis, or blueness of the skin, in babies as a result of low oxygen levels in the blood. This term has traditionally been applied to cyanosis as a result of:. [1] Cyanotic heart disease, which is a category of congenital heart defect that results in low levels of oxygen in the blood. [2]
3. Depending on your nail strength, acrylics may cause a splitting or painful nail plate. Pay close attention to how strong and think your nails are. Extremely thin nails may not be the best for ...