Search results
Results from the WOW.Com Content Network
The earliest and most widely known scientific theory of antidepressant action is the monoamine hypothesis, which can be traced back to the 1950s and 1960s. [ 200 ] [ 201 ] This theory states that depression is due to an imbalance, most often a deficiency, of the monoamine neurotransmitters , namely serotonin , norepinephrine , and/or dopamine .
In the late 1960s and early 1970s, Dexamyl spansules—a clear and green capsule containing green and white "beads"—became popular as a street-drug upper nicknamed "Christmas trees", a reference to its appearance. [6] In his autobiography My Life of Absurdity, author Chester Himes writes of his use of Dexamyl in the mid-1950s. He also writes ...
1950s–1960s Marketed as a psychiatric drug; withdrawn after it became widely used recreationally. Now illegal in most of the world. Mebanazine: 1975 UK Hepatotoxicity, drug intereaction. [3] Methandrostenolone: 1982 France, Germany, UK, US, others Off-label abuse. [3] Methapyrilene: 1979 Germany, UK, US Animal carcinogenicity. [3 ...
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification. Chemical/generic names are listed first, with brand names in parentheses.
Safrazine (Safra) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was introduced as an antidepressant in the 1960s, but has since been discontinued alongside several old generation MAOIs in favor of the invention of RIMAs and more efficacious treatments for depression in general.
Antidepressants are a class of medications used very commonly to treat depression. In fact, nearly 13 percent of people 12 and over in the U.S. used antidepressants in 2017, according to the ...
Antidepressants are most commonly prescribed for people who have major depressive disorder (MDD). MDD is described as feeling depressed, moody or sad all, every day, for at least two weeks.
Talsupram (Lu 5-005 or Lu 5-003 [1]) is a selective norepinephrine reuptake inhibitor (NRI) which was investigated as an antidepressant in the 1960s and 1970s but was never marketed. [2] [3] [4] Along with talopram, it is structurally related to the selective serotonin reuptake inhibitor (SSRI) citalopram. [5]