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  2. Étard reaction - Wikipedia

    en.wikipedia.org/wiki/Étard_reaction

    Benzaldehyde can serve as a precursor for various compounds, including dyes, perfumes, and pharmaceuticals. For example, the first step in the synthesis of ephedrine is condensation of benzaldehyde with nitroethane [citation needed]. Additionally, benzaldehyde is instrumental in the synthesis of phentermine. [10]

  3. Ephedrine - Wikipedia

    en.wikipedia.org/wiki/Ephedrine

    Ephedrine works by inducing the release of norepinephrine and hence indirectly activating the α-and β-adrenergic receptors. [11] Chemically, ephedrine is a substituted amphetamine and is the (1R,2S)-enantiomer of β-hydroxy-N-methylamphetamine. [14] Ephedrine was first isolated in 1885 and came into commercial use in 1926.

  4. Phenylacetylcarbinol - Wikipedia

    en.wikipedia.org/wiki/Phenylacetylcarbinol

    L-pac produced by biotransformation of benzaldehyde. Phenylacetylcarbinol (PAC) is an organic compound that has two enantiomers, one with R-and one with S-configuration. (R)-PAC, which is commonly called l-PAC, is known as a precursor in the synthesis of pharmaceuticals such as ephedrine and pseudoephedrine.

  5. Benzaldehyde - Wikipedia

    en.wikipedia.org/wiki/Benzaldehyde

    Amygdalin 2 H 2 O HCN benzaldehyde 2 × glucose 2 × Benzaldehyde contributes to the scent of oyster mushrooms (Pleurotus ostreatus). Reactions Benzaldehyde is easily oxidized to benzoic acid in air at room temperature, causing a common impurity in laboratory samples. Since the boiling point of benzoic acid is much higher than that of benzaldehyde, it may be purified by distillation. Benzyl ...

  6. Substituted amphetamine - Wikipedia

    en.wikipedia.org/wiki/Substituted_amphetamine

    This synthesis was a by-product of a search for ephedrine, a bronchodilator used to treat asthma extracted exclusively from natural sources. Over-the-counter use of substituted amphetamines was initiated in the early 1930s by the pharmaceutical company Smith, Kline & French (now part of GlaxoSmithKline ), as a medicine ( Benzedrine ) for colds ...

  7. History and culture of substituted amphetamines - Wikipedia

    en.wikipedia.org/wiki/History_and_culture_of...

    Diagnostic impurities are the naphthalenes 1-benzyl-methylnaphthalene and 1,3-dimethyl-2-phenylnaphthalene, [108] arising in the Nagai and Leuckart routes, and cis-or trans-1,2-dimethyl-3-phenylaziridine, ephedrine, or erythro-3,4-dimethyl- 5-phenyloxazolidine, arising in the Nagai and Emde routes; these are absent in the reductive amination ...

  8. Cannizzaro reaction - Wikipedia

    en.wikipedia.org/wiki/Cannizzaro_reaction

    Cannizzaro first accomplished this transformation in 1853, when he obtained benzyl alcohol and potassium benzoate from the treatment of benzaldehyde with potash (potassium carbonate). More typically, the reaction would be conducted with sodium hydroxide or potassium hydroxide , giving the sodium or potassium carboxylate salt of the carboxylic ...

  9. Propiophenone - Wikipedia

    en.wikipedia.org/wiki/Propiophenone

    It is an intermediate in the synthesis of the pharmaceuticals phenmetrazine and propoxyphen. [ 1 ] [ 4 ] [ 5 ] Other drugs made from propiophenone include the following: PDM-35 , Eprazinone , Methcathinone (leading to ephedrine), Trimebutine , Amfepramone , Diphepanol , Metamfepramone , Etoxadrol , Hydroxyphenamate , Phendimetrazine ...