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  2. Investigational device exemption - Wikipedia

    en.wikipedia.org/wiki/Investigational_Device...

    An investigational device exemption (IDE) allows an investigational device (i.e. a device that is the subject of a clinical study [1]) to be used in order to collect safety and effectiveness data required to support a premarket approval (PMA) application or a premarket notification [510(k)] submission to Food and Drug Administration (FDA). [2]

  3. Expanded access - Wikipedia

    en.wikipedia.org/wiki/Expanded_access

    Expanded access or compassionate use is the use of an unapproved drug or medical device under special forms of investigational new drug applications (IND) or IDE application for devices, outside of a clinical trial, by people with serious or life-threatening conditions who do not meet the enrollment criteria for the clinical trial in progress.

  4. Investigational New Drug - Wikipedia

    en.wikipedia.org/wiki/Investigational_new_drug

    If the FDA detects a problem, it may place a clinical hold on the IND, prohibiting the start of the clinical studies until the problem is resolved, as outlined in 21 CFR 312.42. An IND must be labeled "Caution: New Drug – Limited by Federal (or United States) law to investigational use," per 21 CFR 312.6

  5. Food and Drug Administration Safety and Innovation Act

    en.wikipedia.org/wiki/Food_and_Drug...

    The Food and Drug Administration Safety and Innovation Act of 2012 (FDASIA) is a piece of American regulatory legislation signed into law on July 9, 2012.It gives the United States Food and Drug Administration (FDA) the authority to collect user fees from the medical industry to fund reviews of innovator drugs, medical devices, generic drugs and biosimilar biologics.

  6. Biologics license application - Wikipedia

    en.wikipedia.org/wiki/Biologics_License_Application

    A biologics license application (BLA) is defined by the U.S. Food and Drug Administration (FDA) as follows: The biologics license application is a request for permission to introduce, or deliver for introduction, a biologic product into interstate commerce (21 CFR 601.2). The BLA is regulated under 21 CFR 600 – 680.

  7. Genealogy testing IDs suspect in 1975 assault of 3 young ...

    www.aol.com/news/genealogy-testing-identifies...

    At the time, an investigation into the suspect led to a composite sketch, and several leads were followed and suspects ruled out. Eventually the case went cold. Looking at the case again.

  8. Food and Drug Administration (Philippines) - Wikipedia

    en.wikipedia.org/wiki/Food_and_Drug...

    The Food and Drug Administration (FDA) of the Philippines, formerly the Bureau of Food and Drugs (BFAD / ˈ b iː f æ d /; 1982–2009), is a health regulatory agency under the Department of Health created on 1963 by Republic Act No. 3720, amended on 1987 by Executive Order 175 otherwise known as the "Food, Drugs and Devices, and Cosmetics Act", and subsequently reorganized by Republic Act No ...

  9. Philippines' investigation into drugs war will be "fair ... - AOL

    www.aol.com/news/philippines-investigation-drugs...

    The Philippines has said its investigation into killings during former President Rodrigo Duterte's war on drugs will be "impartial", a day after its attempt to block a similar probe by the ...