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Cefoperazone/sulbactam is a combination drug used as an antibiotic. It is effective for the treatment of urinary tract infections . [ 2 ] It contains cefoperazone , a β-lactam antibiotic , and sulbactam , a β-lactamase inhibitor , which helps prevent bacteria from breaking down cefoperazone.
Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]
N-Methylserotonin is a tryptamine alkaloid. Chemically, it is a derivative of serotonin in which a methyl group resides at its alkyl amine. It is also called N ω-methylserotonin (N ω-methyl-5-hydroxytryptamine) to distinguish it from tryptamine-derived compounds in which a methyl group is bonded to the nitrogen atom of the indole group.
Azasetron is an antiemetic which acts as a 5-HT 3 receptor antagonist, pK i = 9.27 [1] It is used in the management of nausea and vomiting induced by cancer chemotherapy (such as cisplatin chemotherapy). Azasetron hydrochloride is given in a usual dose of 10 mg once daily by mouth or intravenously.
Viloxazine acts as a selective norepinephrine reuptake inhibitor (NRI). [6] [1] [5] The immediate-release form has an elimination half-life of 2.5 hours [6] [2] while the half-life of the extended-release form is 7 hours. [1] Viloxazine was first described by 1972 [10] and was marketed as an antidepressant in Europe in 1974.
Metopimazine is an approved prescription drug in France under the brand name Vogalene® [8] that has been used for the treatment of nausea and vomiting. [9] Vogalene® is available under different forms, including 15 mg capsules, 7.5 mg orally disintegrating tablets, 5 mg suppository, 0.1% oral liquid, and a 10 mg/mL intravenous (IV) solution approved for the prevention of chemotherapy-induced ...
Osemozotan (MKC-242) is a selective 5-HT 1A receptor agonist with some functional selectivity, acting as a full agonist at presynaptic and a partial agonist at postsynaptic 5-HT 1A receptors. [ 1 ] 5-HT 1A receptor stimulation influences the release of various neurotransmitters including serotonin , dopamine , norepinephrine , and acetylcholine .
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