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This protective agent was also found to be associated with the survival of cochlear spiral ganglion neurones after hearing loss or deafness. [35] Audiological management can be implemented, for example, by providing hearing aids. In more seriously affected patients, cochlear implantation may be considered and discussed with the patient.
The hearing loss caused by chemicals can be very similar to a hearing loss caused by excessive noise. A 2018 informational bulletin by the US Occupational Safety and Health Administration (OSHA) and the National Institute for Occupational Safety and Health (NIOSH) introduces the issue, provides examples of ototoxic chemicals, lists the ...
Dantrolene sodium, sold under the brand name Dantrium among others, is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. [ 5 ] [ 6 ] [ 7 ] It achieves this by inhibiting Ca 2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors . [ 8 ]
MRI and CT scans can be useful to identify the pathology of many causes of hearing loss. Hearing loss is categorized by severity, type, and configuration. Furthermore, a hearing loss may exist in only one ear (unilateral) or in both ears (bilateral). Hearing loss can be temporary or permanent, sudden or progressive.
Others may cause permanent hearing loss. [37] The most important group is the aminoglycosides (main member gentamicin) and platinum based chemotherapeutics such as cisplatin and carboplatin. [38] [39] In 2007, the U.S. Food and Drug Administration (FDA) warned about possible sudden hearing loss from PDE5 inhibitors, which are used for erectile ...
Chemically induced hearing loss (CIHL) is a potential result of occupational exposures. Certain chemical compounds may have ototoxic effects. Exposure to organic solvents, heavy metals, and asphyxiants such as carbon monoxide can all cause hearing loss. [20] [21] These chemicals can be inhaled, ingested, or absorbed through the skin. Damage can ...
In a new interview with the Sunday Times, the legendary singer-songwriter, 81, opened up about losing part of his hearing while working on his latest album, Seven Psalms, which has put any ...
Baclofen, diazepam and dantrolene remain the three most commonly used pharmacologic agents in the treatment of spastic hypertonia. Baclofen is generally the drug of choice for spinal cord types of spasticity, while sodium dantrolene is the only agent which acts directly on muscle tissue. Tizanidine is also available.