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Symptoms can start within an hour of exposure, and can last for several months. [1] [3] [5] Early symptoms are usually nausea, vomiting and loss of appetite. [1] In the following hours or weeks, initial symptoms may appear to improve, before the development of additional symptoms, after which either recovery or death follow. [1]
A death rattle is noisy breathing that often occurs in someone near death. [1] Accumulation of fluids such as saliva and bronchial secretions in the throat and upper airways is the cause. [ 2 ] Those who are dying may lose their ability to swallow and may have increased production of bronchial secretions, resulting in such an accumulation. [ 3 ]
That is, in whispered pectoriloquy, the repeated words are whispered at low volume, and in bronchophony, they are spoken at normal volume. The clinical observation being determined is whether or not an increase in volume is heard at the clinician's stethoscope over the lung field being auscultated which would indicate lung consolidation.
Infant prematurity is the factor most commonly associated with pulmonary hemorrhage. Other associated factors are those that predisposed to perinatal asphyxia or bleeding disorders, including toxemia of pregnancy, maternal cocaine use, erythroblastosis fetalis, breech delivery, hypothermia, infection (like pulmonary tuberculosis), Infant respiratory distress syndrome (IRDS), administration of ...
Lymphocytic interstitial pneumonia (LIP) is a syndrome secondary to autoimmune and other lymphoproliferative disorders. Symptoms include fever, cough, and shortness of breath. Lymphocytic interstitial pneumonia applies to disorders associated with both monoclonal or polyclonal gammopathy. [1]
In Susac's syndrome, an autoimmune response damages the blood vessels of the brain, retina and cochlea, leading to a loss of neurological functions. Patients with the syndrome had hearing and vision loss and were found to have higher concentrations of lymphocytes and proteins in their cerebrospinal fluid.
The cause of TRALI is currently not fully understood. 80–85% of cases are thought to be immune mediated. [5] [6] Antibodies directed toward human leukocyte antigens (HLA) or human neutrophil antigens (HNA) have been implicated, with transfused antibodies shown to bind antigens expressed on pulmonary endothelial cells to initiate acute inflammation in the lungs.
Lymphoproliferative disorders are a set of disorders characterized by the abnormal proliferation of lymphocytes into a monoclonal lymphocytosis. The two major types of lymphocytes are B cells and T cells, which are derived from pluripotent hematopoietic stem cells in the bone marrow.