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One explanation for the connection between inflammation and depression symptoms, is that depression is a disorder that stems from immune responses across the body. [13] Due in large part to the systems that bring them about both involving the same pro-inflammatory cytokines, the suggestion is that strong or prolonged immune responses allow for ...
Mental health journalist and author John McManamy argues that although psychiatrists do not explicitly deal with the condition of apathy, it is a psychological problem for some depressed people, in which they get a sense that "nothing matters", the "lack of will to go on and the inability to care about the consequences".
Anhedonia is a diverse array of deficits in hedonic function, including reduced motivation or ability to experience pleasure. [1] While earlier definitions emphasized the inability to experience pleasure, anhedonia is currently used by researchers to refer to reduced motivation, reduced anticipatory pleasure (wanting), reduced consummatory pleasure (liking), and deficits in reinforcement learning.
An estimated 4.4 percent of the global population has depression, according to a report released by the UN World Health Organization (WHO), which shows an 18 percent increase in the number of people living with depression between 2005 and 2015. [66] [67] [68] Depression is a major mental-health cause of disease burden.
Amotivational syndrome is a chronic psychiatric disorder characterized by signs that are linked to cognitive and emotional states such as detachment, blunted emotion and drives, executive functions like memory and attention, [1] disinterest, passivity, apathy, and a general lack of motivation.
Emotional blunting is a symptom of MDD, [6] as depression is negatively correlated with emotional (both positive and negative) experiences. [14] Schizophrenia often occurs with negative symptoms, extrapyramidal signs (EPS), and depression. The latter overlaps with emotional blunting and is shown to be a core part of the present effects. [15]
For people with treatment-resistant depression, those who received CBT plus medication were three times more likely to get at least a 50 percent improvement in their symptoms than those who ...
Physical illnesses, including hypothyroidism and mitochondrial disease, can also trigger depressive symptoms. [4] [5] Neural circuits implicated in depression include those involved in the generation and regulation of emotion, as well as in reward. Abnormalities are commonly found in the lateral prefrontal cortex whose putative function is ...
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