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  2. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    The result is that apixaban generics will most likely not be available in the United States until at least 2026, but possibly 2031. [19] In July 2022, the Canadian generic drug company, Apotex Inc., obtained approval for marketing of apixaban. [40] [41] Pfizer reported revenue of US$6.747 billion for Eliquis in 2023. [42]

  3. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

  4. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]

  5. Healthgrades - Wikipedia

    en.wikipedia.org/wiki/Healthgrades

    Healthgrades evaluates hospitals solely on risk-adjusted mortality and in-hospital complications. [17] Its website evaluates roughly 500 million claims from federal and private reviews and data to rate and rank doctors based on complication rates at the hospitals where they practice, experience, and patient satisfaction. [8]

  6. BBB Reveals America's Most Complained-About Businesses - AOL

    www.aol.com/news/2012-03-02-bbb-reveals-americas...

    Topping the complaint list were cell-phone companies, with 38,420 complaints, up 41% over 2010. After that, the list includes (in order of number of gripes): new-car dealers

  7. List of hospitals in Canada - Wikipedia

    en.wikipedia.org/wiki/List_of_hospitals_in_Canada

    For a list sorted by facility name see List of hospitals in Alberta. Banff. Banff Mineral Springs Hospital; Bassano. Bassano Health Centre; Calgary. Alberta Children's Hospital (ACH) Foothills Medical Centre (FMC) Peter Lougheed Centre (PLC) Rockyview General Hospital (RGH) Sheldon M. Chumir Centre; South Health Campus (SHC) Tom Baker Cancer ...

  8. Andexanet alfa - Wikipedia

    en.wikipedia.org/wiki/Andexanet_alfa

    Andexanet alfa, sold under the brand name Andexxa among others, is an antidote for the medications rivaroxaban and apixaban, when reversal of anticoagulation is needed due to uncontrolled bleeding. [8] It has not been found to be useful for other factor Xa inhibitors. [9] It is given by injection into a vein. [9]

  9. Royal College of Physicians and Surgeons of Canada

    en.wikipedia.org/wiki/Royal_College_of...

    The Royal College of Physicians and Surgeons of Canada (French: Collège royal des médecins et chirurgiens du Canada) is a regulatory college which acts as a national, nonprofit organization established in 1929 by a special Act of Parliament to oversee the medical education of specialists in Canada.