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A dermatofibroma is associated with the dimple sign; by applying lateral pressure, there is a central depression of the dermatofibroma. Although typical dermatofibromas cause little or no discomfort, itching and tenderness can occur. Dermatofibromas can be found anywhere on the body, but most often they are found on the legs and arms. [5]
In an earlier (2014) retrospective review of 225 cases treated for DFSP-FS, 29.8% developed post-surgical recurrent disease (median time after surgery: 0.9-7.8 years), 14.4% had or developed metastatic disease, and 14.7% died from their disease (median time after surgery: 14.7 years).
Dermatofibrosarcoma protuberans begins as a minor firm area of skin most commonly about to 1 to 5 cm in diameter. It can resemble a bruise, birthmark, or pimple. It is a slow-growing tumor and is usually found on the torso but can occur anywhere on the body. [7] About 90% of DFSPs are low-grade sarcomas.
They can grow in all organs, arising from mesenchyme tissue. The term "fibroblastic" or "fibromatous" is used to describe tumors of the fibrous connective tissue. When the term fibroma is used without modifier, it is usually considered benign, with the term fibrosarcoma reserved for malignant tumors.
While breast cancer is still most common in middle-aged and older women, according to the American Cancer Society, recent research shows that rates have increased in younger women over the past ...
The term fibromatosis refers to a group of soft tissue tumors [1] which have certain characteristics in common, including absence of cytologic and clinical malignant features, a histology consistent with proliferation of well-differentiated fibroblasts, an infiltrative growth pattern, and aggressive clinical behavior with frequent local recurrence.
[1] [2] The blue colour is caused by the pigment being deep in the skin. [4] Diagnosis is by visualisation and dermoscopy. [4] A biopsy is sometimes performed, or the whole lesion surgically removed. [3] The outcome is generally good but there is a small chance of cancerous transformation. [3] Differential diagnosis includes dermatofibroma and ...
Gardner fibroma (GF) (also termed Gardner-associated fibroma [1]) is a benign fibroblastic tumor (i.e. a tumor containing fibroblasts, the most common cell type in connective tissue). GF tumors typically develop in the dermis (i.e. layer of skin underneath the epidermis ) and adjacent subcutaneous tissue lying just below the dermis. [ 2 ]