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The strongest risk factor for developing asthma is a history of atopic disease; [66] with asthma occurring at a much greater rate in those who have either eczema or hay fever. [80] Asthma has been associated with eosinophilic granulomatosis with polyangiitis (formerly known as Churg–Strauss syndrome), an autoimmune disease and vasculitis . [ 81 ]
The mechanisms behind allergic asthma—i.e., asthma resulting from an immune response to inhaled allergens—are the best understood of the causal factors. In both people with asthma and people who are free of the disease, inhaled allergens that find their way to the inner airways are ingested by a type of cell known as antigen-presenting ...
Hartert studies the predictive factors of asthma development and the causal role of respiratory viral infections. [5] During infancy, the viral pathogens that are the strongest risk factors for asthma are human orthopneumovirus and human rhinovirus . [ 6 ]
In a review of studies on the prevalence of asthma among migrant populations, those born in high-income countries were found to have higher rates of asthma than migrants. Second-generation migrants had a higher risk of asthma than first-generation migrants, and the prevalence of asthma increases with longer time of residence in the host country ...
Asthma with obesity, insulin resistance, vitamin D deficiency, or metabolic syndrome is now recognised as a distinct T2-low phenotype of severe asthma refractory to inhaled corticosteroids. Obesity is a known risk factor for asthma development and exacerbation.
"Although excess body weight is the major predisposing factor for sleep apnea, many cases of sleep apnea are related to other factors such as the structure of the jaw and upper airway," AASM said ...
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