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One of the first major discoveries relevant to the field of pulmonology was the discovery of pulmonary circulation.Originally, it was thought that blood reaching the right side of the heart passed through small 'pores' in the septum into the left side to be oxygenated, as theorized by Galen; however, the discovery of pulmonary circulation disproves this theory, which had previously been ...
The pulmonary circulation is a division of the circulatory system in all vertebrates. The circuit begins with deoxygenated blood returned from the body to the right atrium of the heart where it is pumped out from the right ventricle to the lungs.
On the other hand, gravity causes a gradient in blood pressure between the top and bottom of the lung of 20 mmHg in the erect position (roughly half of that in the supine position). Overall, mean pulmonary venous pressure is ~5 mmHg. Local venous pressure falls to -5 at the apexes and rises to +15 mmHg at the bases, again for the erect lung.
The unit described as the secondary pulmonary lobule is the lobule most referred to as the pulmonary lobule or respiratory lobule. [25]: 489 [31] This lobule is a discrete unit that is the smallest component of the lung that can be seen without aid. [29] The secondary pulmonary lobule is likely to be made up of between 30 and 50 primary lobules ...
The pulmonary circulation as it passes from the heart. Showing both the pulmonary and bronchial arteries. The pulmonary circulation is the part of the circulatory system in which oxygen-depleted blood is pumped away from the heart, via the pulmonary artery, to the lungs and returned, oxygenated, to the heart via the pulmonary vein.
Ventilation refers to the in-and-out movement of air of the lungs and perfusion is the circulation of blood in the pulmonary capillaries. [1] In mammals, physiological respiration involves respiratory cycles of inhaled and exhaled breaths .
The differences between the atmospheric and intrapulmonary pressures, driving air in and out of the lungs during the breathing cycle, are in the region of only 2–3 kPa. [18] [19] A doubling or more of these small pressure differences could be achieved only by very major changes in the breathing effort at high altitudes.
In addition to the redistribution of blood in the body, most cases of dyspnea are accompanied by an increase in the overall work of breathing, often caused by abnormal pulmonary mechanisms. [5] The perception of dyspnea is theorized to be a complicated connection between peripheral receptors, neural pathways, and the central nervous system.