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Magnetic resonance imaging (MRI) scans to assess brain structure, connectivity, and the extent of white matter disease; Positron emission tomography (PET) scans to assess how well the brain uses glucose, and the extent of amyloid plaques and tau tangles. Neuropathological examination if a participant dies and has consented to autopsy.
Neuroimaging software is used to study the structure and function of the brain. To see an NIH Blueprint for Neuroscience Research funded clearinghouse of many of these software applications, as well as hardware, etc. go to the NITRC web site. 3D Slicer Extensible, free open source multi-purpose software for visualization and analysis.
Standard brain maps such as the Talairach-Tournoux or templates from the Montréal Neurological Institute (MNI) allow researchers from across the world to compare their results. Images can be smoothed to make the data less noisy (similar to the 'blur' effect used in some image-editing software) by which voxels are averaged with their neighbours ...
In the early 2000s, the field of neuroimaging reached the stage where limited practical applications of functional brain imaging have become feasible. The main application area is crude forms of brain–computer interface. The world record for the spatial resolution of a whole-brain MRI image was a 100-micrometer volume (image) achieved in 2019.
Averaging is necessary because of the complex spectral structures and relatively low concentrations of many brain metabolites, which result in a low signal-to-noise ratio (SNR) in MRS of a living brain. fMRS differs from MRS by acquiring not one but multiple spectra at different time points while the participant is inside the MRI scanner.
Refined by a neuroimaging approach and a training protocol, They fashioned a non-invasive EEG based brain-computer interface to control the flight of a virtual helicopter in 3-dimensional space, based upon motor imagination. [115] In June 2013 they announced a technique to guide a remote-control helicopter through an obstacle course. [116]
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Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. [1] [2] This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area of the brain is in use, blood flow to that region also increases. [3]