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Other side effects include heart problems, increased risk of infection, and lung inflammation. [11] There are concerns that use during pregnancy may cause birth defects. [12] [11] Paclitaxel is in the taxane family of medications. [13] It works by interference with the normal function of microtubules during cell division. [11]
[12] [25] As with all chemotherapy, adverse effects are common, and many side effects have been documented. [17] [19] Because docetaxel is a cell-cycle-specific agent, it is cytotoxic to all dividing cells in the body. [26] This includes tumour cells as well as hair follicles, bone marrow and other germ cells.
By conducting a meta-analysis of four large breast cancer trials including nearly 3,000 patients, the researchers have discovered that an abnormality on chromosome 17, called CEP17, is associated with a worse outcome for patients, but also that its presence is a highly significant indicator that the tumor will respond to anthracyclines.
A week after the third dose, she was at a restaurant with her best friend when her speech slurred and she had a seizure. ... new drug — much the way nausea and hair loss are side effects of ...
The women used 15% minoxidil for 12 weeks. At the end of the treatment period, 60 percent of participants experienced hair growth. Another bonus was that none of the women reported adverse events ...
Cytoskeletal drugs are small molecules that interact with actin or tubulin.These drugs can act on the cytoskeletal components within a cell in three main ways. Some cytoskeletal drugs stabilize a component of the cytoskeleton, such as taxol, which stabilizes microtubules, or Phalloidin, which stabilizes actin filaments.
None of the women completed all tasks all days, and that’s okay, researchers wrote. Improvements in biological age were seen among women who adhered to the program an average of 82% of the time.
Therapy with combination of two or more drugs which have various binding sites and/or different mechanism of action but have non overlapping adverse effects. This would allow use of drugs in low concentration what reduce strength of side effects associated with high doses of anticancer agents.