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Inhaled nitric oxide is a gas that is inhaled. [1] It was initially described in 1987 as an "endothelial-derived relaxing factor" and has since been used to treat pulmonary disorders. [3] It works by relaxing smooth muscle to widen (dilate) blood vessels, especially in the lungs. [1] Inhaled nitric oxide selects only pulmonary smooth muscles.
Nitric oxide is a vasodilator, meaning it essentially tells blood vessels when to open or close, improving the flow of oxygen into the body via your heart. Doctors Are Looking At Inhaled Nitric ...
Nitric oxide is absorbed systemically after inhalation. Most of it moves across the pulmonary capillary bed where it combines with hemoglobin that is 60% to 100% oxygen-saturated. Nitrate has been identified as the predominant nitric oxide metabolite excreted in the urine, accounting for >70% of the nitric oxide dose inhaled.
Until the 1980s, nitric oxide, a product of fossil fuel combustion, was thought only to play a role the detrimental effects of air pollution on the respiratory tract. [17] In 1987, experiments with coronary arteries showed that nitric oxide was the long sought endothelium-derived relaxing factor .
Nitric oxide is a vasodilator, meaning it essentially tells blood vessels when to open or close, improving the flow of oxygen into the body via your heart. Doctors Studying Nitric Oxide Gas As ...
Nitric oxide (nitrogen oxide or nitrogen monoxide [1]) is a colorless gas with the formula NO. It is one of the principal oxides of nitrogen . Nitric oxide is a free radical : it has an unpaired electron , which is sometimes denoted by a dot in its chemical formula ( • N=O or • NO).
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