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Dihydrotestosterone, also known as (DHT) will differentiate the remaining male characteristics of the external genitalia. [11] Further sex differentiation of the external genitalia occurs at puberty, when androgen levels again become disparate. Male levels of testosterone directly induce growth of the penis, and indirectly (via DHT) the prostate.
Adults with "late onset", or those without a childhood history of said behavior, are more likely to have a non-homosexual orientation. [56] Prenatal androgen exposure has been associated with an increased chance of patient-initiated gender reassignment to male after being initially raised as female in early childhood or infancy.
Sexual differentiation is the process of development of the sex differences between males and females from an undifferentiated zygote. [1] [2] Sex determination is often distinct from sex differentiation; sex determination is the designation for the development stage towards either male or female, while sex differentiation is the pathway towards the development of the phenotype.
[14] [15] Although variations exist and there may be a degree of overlap between typically male or female traits, [14] [15] the pelvis is the most dimorphic bone of the human skeleton and is therefore likely to be accurate when using it to ascertain a person's sex. [15] It differs both in overall shape and structure.
The male "growth spurt" also begins later, accelerates more slowly, and lasts longer before the epiphyses fuse. Although males are on average 2 centimetres (0.8 in) shorter than females before puberty begins, adult men are on average about 13 centimetres (5.1 in) taller than women. Most of this sex difference in adult heights is attributable to ...
Male primary sex characteristics are the penis, the scrotum and the ability to ejaculate when matured. Female primary sex characteristics are the vulva, vagina, uterus, fallopian tubes, cervix, and the ability to give birth and menstruate when matured. [1] Hormones that express sexual differentiation in humans include: estrogens such as estradiol
XX male syndrome, also known as de la Chapelle syndrome, is a rare intersex condition in which an individual with a 46,XX karyotype develops a male phenotype. [2] Synonyms for XX male syndrome include 46,XX testicular difference of sex development (or 46,XX DSD) [3] [4] [5] [6]
In mammals, evidence of CASI in brain cells has implications for understanding sex differences in neural development, cognition, and behavior. CASI may contribute to innate sex-specific behaviors and provide new perspectives on the biological basis of neurodevelopmental disorders that exhibit sex-biased prevalence, such as autism spectrum disorder.