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1952: an X-ray diffraction image of DNA was taken by Raymond Gosling in May 1952, a student supervised by Rosalind Franklin. [30] 1953: DNA structure is resolved to be a double helix by James Watson, Francis Crick and Maurice Wilkins. [31] 1955: Alexander R. Todd determined the chemical makeup of nitrogenous bases.
1972 – The DNA composition of chimpanzees and gorillas is discovered to be 99% similar to that of humans. 1973 – Stanley Norman Cohen and Herbert Boyer perform the first successful recombinant DNA experiment, using bacterial genes. [6] 1974 – Scientists invent the first biocement for industrial applications.
Using these x-rays and information already known about the chemistry of DNA, James D. Watson and Francis Crick demonstrated the molecular structure of DNA in 1953. [22] [23] Together, these discoveries established the central dogma of molecular biology, which states that proteins are translated from RNA which is transcribed by
In 1953, James Watson and Francis Crick discovered the double helical structure of the DNA molecule based on the discoveries made by Rosalind Franklin. [5] In 1961, François Jacob and Jacques Monod demonstrated that the products of certain genes regulated the expression of other genes by acting upon specific sites at the edge of those genes.
1940 – Donald Griffin and Robert Galambos announced their discovery of echolocation by bats. 1942 – Max Delbrück and Salvador Luria demonstrated that bacterial resistance to virus infection is caused by random mutation and not adaptive change. 1944 – Oswald Avery shows that DNA carried the hereditary information in pneumococcus bacteria.
Important advances included the discovery of restriction enzymes and DNA ligases, the ability to design plasmids and technologies like polymerase chain reaction and sequencing. Transformation of the DNA into a host organism was accomplished with the invention of biolistics, Agrobacterium-mediated recombination and microinjection.
The timeline begins at the Bronze Age, as it is difficult to give even estimates for the timing of events prior to this, such as of the discovery of counting, natural numbers and arithmetic. To avoid overlap with timeline of historic inventions , the timeline does not list examples of documentation for manufactured substances and devices unless ...
A panel of DNA samples from old cases was collected and coded, and was analyzed blind by Saiki using the HLA DQα assay. When the code was broken, all of the evidence and perpetrators matched. Blake and Erlich's group used the technique almost immediately in Pennsylvania v. Pestinikas, [28] the first use of PCR in