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In some cases the level or exposure-time may be critical, with some substances only becoming neurotoxic in certain doses or time periods. Some of the most common naturally occurring brain toxins that lead to neurotoxicity as a result of long term drug use are amyloid beta (Aβ), glutamate, dopamine, and oxygen radicals.
The blood–brain barrier (BBB) is one critical example of protection which prevents toxins and other adverse compounds from reaching the brain. [22] As the brain requires nutrient entry and waste removal, it is perfused by blood flow.
The cranial cavity, also known as intracranial space, is the space within the skull that accommodates the brain.The skull is also known as the cranium. [1] The cranial cavity is formed by eight cranial bones known as the neurocranium that in humans includes the skull cap and forms the protective case around the brain.
Image of the human brain showing sulci, gyri, and fundi shown in a Coronal section. Specific terms are used to represent the gross anatomy of the brain: A gyrus is an outward folding of the brain, for example the precentral gyrus. A sulcus is an inward fold, or valley in the brain's surface - for example the central sulcus. Additional terms ...
Toxic encephalopathy is a neurologic disorder caused by exposure to neurotoxic organic solvents such as toluene, following exposure to heavy metals such as manganese, as a side effect of melarsoprol treatment for African trypanosomiasis, adverse effects to prescription drugs, or exposure to extreme concentrations of any natural toxin such as cyanotoxins found in shellfish or freshwater ...
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A new study in mice suggests the hypothesis that brain-cleansing occurs during sleep may be inaccurate. The findings show that mice cleaned more toxins and metabolites from the brain when they ...
The central canal below at the ventricular system of the brain, beginning at a region called the obex where the fourth ventricle, a cavity present in the brainstem, narrows. The central canal is located in the anterior third of the spinal cord in the cervical and thoracic regions. In the lumbar spine it enlarges