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In most cases, pancreas transplantation is performed on people with type 1 diabetes with end-stage renal disease, brittle diabetes, and hypoglycaemic unawareness. Other type 2 diabetics can benefit from a pancreas transplant. The indications for a type 2 diabetic are a BMI < 30 kg/m2 and low overall insulin requirement (< 1 U/kg/day).
Richard C. Lillehei (10 December 1927 - 1 April 1981) was an American transplant surgeon who performed the world's first successful simultaneous pancreas-kidney transplant in 1966 (sometimes quoted as 1967) and the first known human intestinal transplantation.
Five-year follow-up after clinical islet transplantation. Diabetes. 2005 Jul;54(7):2060-9. Sutherland DE, Gruessner RW, Gruessner AC. Pancreas transplantation for treatment of diabetes mellitus. World J Surg. 2001 Apr;25(4):487-96. Shapiro AMJ, Ricordi C, Hering BJ et al. International trial of the Edmonton protocol for islet transplantation. N ...
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Among common consequences of complete or nearly complete pancreatectomy are deficiencies of pancreatic endocrine or exocrine function requiring replacement of insulin or digestive enzymes. The patient immediately develops type 1 diabetes, with little hope for future type 1 diabetes treatments involving the restoration of endocrine function to a ...
This page was last edited on 5 January 2006, at 21:14 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may ...
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