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Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. It is also used as a treatment for depression and in pain management. [19] Ketamine is an NMDA receptor antagonist which accounts for most of its psychoactive effects. [20]
Ketamine (also known as Ket, K, Special K, vitamin K, Kitty, and others) is a classical dissociative substance of the arylcyclohexylamine class. It is perhaps the best-known and archetypal member of the dissociatives, a diverse group which includes PCP, methoxetamine, DXM, and nitrous oxide.
Ketamine is a dissociative anesthetic. It is a type of drug a doctor might give to put someone to sleep for an operation. Ketamine can also be used as a painkiller and a bronchodilator (which makes it easier for air to get into the lungs). [1]
What is ketamine? Ketamine is an NMDA receptor antagonist, meaning it blocks the N-methyl-D-aspartate neurotransmitter in the brain. It was developed in the 1960s and used as a battlefield anesthetic in the Vietnam War, as well as clinically in health care settings.
Ketamine is FDA-approved for use as an anesthetic in humans and animals. A drug made from ketamine, called esketamine, is FDA-approved for treatment-resistant depression. Ketamine has also been illegally manufactured for decades as a recreational drug.
Ketamine is an anesthetic, used to induce a loss of consciousness and relieve pain. It is commonly abused for its hallucinogenic and dissociative effects and, controversially, it may be...
Meta-analysis also suggests that Ketamine does not increase ICP and provides favorable hemodynamics. Neurologic Injury. Metaanalysis has shown that when ketamine is used in the presence of controlled ventilation, in conjunction with anaesthetics which reduce cerebral metabolism such as GABA receptor agonists, ICP is not increased. Pharmacology
Ketamine is a general anesthetic agent related structurally to the hallucinogen phencyclidine (PCP). Ketamine was first synthesized in 1962 by an American scientist who was searching for a new anesthetic to replace PCP, which was not suitable for use in humans because of the severe hallucinogenic effects it produced.