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  2. Eukaryotic DNA replication - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_DNA_replication

    The process of semiconservative replication for the site of DNA replication is a fork-like DNA structure, the replication fork, where the DNA helix is open, or unwound, exposing unpaired DNA nucleotides for recognition and base pairing for the incorporation of free nucleotides into double-stranded DNA.

  3. Cell cycle - Wikipedia

    en.wikipedia.org/wiki/Cell_cycle

    A diagram of the mitotic phases. Mitosis is the process by which a eukaryotic cell separates the chromosomes in its cell nucleus into two identical sets in two nuclei. [8] During the process of mitosis the pairs of chromosomes condense and attach to microtubules that pull the sister chromatids to opposite sides of the cell. [9]

  4. Control of chromosome duplication - Wikipedia

    en.wikipedia.org/wiki/Control_of_chromosome...

    At the sequence level, AT rich elements and CpG islands have been found at origins, but their importance or role is not yet clear. At the level of DNA structure, bent DNA and loop formation have been identified as origin features. Features identified at the chromatin level include nucleosome free regions, histone acetylation and DNAse sensitive ...

  5. Replisome - Wikipedia

    en.wikipedia.org/wiki/Replisome

    DNA is a duplex formed by two anti-parallel strands. Following Meselson-Stahl, the process of DNA replication is semi-conservative, whereby during replication the original DNA duplex is separated into two daughter strands (referred to as the leading and lagging strand templates). Each daughter strand becomes part of a new DNA duplex.

  6. Pre-replication complex - Wikipedia

    en.wikipedia.org/wiki/Pre-replication_complex

    Once a cellular division occurs, the pre-RC must revert back to the bORC to ensure that only one round of DNA replication occurs during division. In E. coli, there are 11 GATC sites in the oriC that undergo hemimethylation during DNA replication. The protein SeqA binds to these sites preventing remethylation and blocking the binding of DnaA to ...

  7. Gene structure - Wikipedia

    en.wikipedia.org/wiki/Gene_structure

    Each element has a specific function in the multi-step process of gene expression. The sequences and lengths of these elements vary, but the same general functions are present in most genes. [ 2 ] Although DNA is a double-stranded molecule, typically only one of the strands encodes information that the RNA polymerase reads to produce protein ...

  8. Eukaryotic transcription - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_transcription

    Eukaryotic Transcription. Eukaryotic transcription is the elaborate process that eukaryotic cells use to copy genetic information stored in DNA into units of transportable complementary RNA replica. [1] Gene transcription occurs in both eukaryotic and prokaryotic cells. Unlike prokaryotic RNA polymerase that initiates the transcription of all ...

  9. Minichromosome maintenance - Wikipedia

    en.wikipedia.org/wiki/Minichromosome_Maintenance

    MCM2-7 is required for both DNA replication initiation and elongation; its regulation at each stage is a central feature of eukaryotic DNA replication. [3] During G1 phase, the two head-to-head Mcm2-7 rings serve as the scaffold for the assembly of the bidirectional replication initiation complexes at the replication origin.