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Dexmedetomidine, under the brand name Dexdomitor (Orion Corporation), was approved in the European Union for use in cats and dogs in 2002, for sedation and induction of general anesthesia. [51] The FDA approved dexmedetomidine for use in dogs in 2006 and cats in 2007.
Medetomidine is a racemic mixture of two optical or stereoisomers, levomedetomidine and dexmedetomidine. [4] The latter causes the alpha 2- adrenergic agonist effects. [5] It is often used as the hydrochloride salt, medetomidine hydrochloride, a crystalline white solid that can be administered as an intravenous drug solution with sterile water.
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This is an accepted version of this page This is the latest accepted revision, reviewed on 23 February 2025. Book containing line art, to which the user is intended to add color For other uses, see Coloring Book (disambiguation). Filled-in child's coloring book, Garfield Goose (1953) A coloring book is a type of book containing line art to which people are intended to add color using crayons ...
Since untreated feline infectious peritonitis (FIP) is fatal in almost all cases [9] and in most countries there are no approved treatments available, GS-441524 has reportedly been sold illegally worldwide on the black market and used by pet owners to treat affected cats, although Gilead Sciences has refused to license the drug for veterinary use.
The minimum lethal dose in dogs is over 5 mg/m 2; dogs have tolerated getting ten times the standard dose. [9] [33] Signs of overdose include panting, trembling, vomiting, and diarrhea, as well as increased blood levels of creatine kinase, aspartate transaminase, and alanine transaminase. Dogs who received atipamezole without first receiving ...
Feline hepatic lipidosis, also known as feline fatty liver syndrome, is one of the most common forms of liver disease of cats. [1] The disease officially has no known cause, though obesity is known to increase the risk. [2] The disease begins when the cat stops eating from a loss of appetite, forcing the liver to convert body fat into usable ...
Dexmedetomidine has the trade name of Dexdomitor. It is frequently used in dogs and cats both for sedation or as a pre-anesthetic. It is licensed for use in the United states by Pfizer Animal Health. In my experience, it is rarely used as a single agent. It has potent synergistic characteristics when used with an opiod.
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