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The FASTA package is available from the University of Virginia [3] and the European Bioinformatics Institute. [4] The FASTA file format used as input for this software is now largely used by other sequence database search tools (such as BLAST) and sequence alignment programs (Clustal, T-Coffee, etc.).
The format allows for sequence names and comments to precede the sequences. It originated from the FASTA software package and has since become a near-universal standard in bioinformatics. [4] The simplicity of FASTA format makes it easy to manipulate and parse sequences using text-processing tools and scripting languages.
Sequence-context specific BLAST, more sensitive than BLAST, FASTA, and SSEARCH. Position-specific iterative version CSI-BLAST more sensitive than PSI-BLAST: Protein: Angermueller C, Biegert A, Soeding J [3] 2013 CUDASW++ GPU accelerated Smith Waterman algorithm for multiple shared-host GPUs: Protein: Liu Y, Maskell DL and Schmidt B: 2009/2010 ...
The fourth is a great example of how interactive graphical tools enable a worker involved in sequence analysis to conveniently execute a variety if different computational tools to explore an alignment's phylogenetic implications; or, to predict the structure and functional properties of a specific sequence, e.g., comparative modelling.
BASys (Bacterial Annotation System) is a tool for automated annotation of bacterial genomic (chromosomal and plasmid) sequences including gene/protein names, GO functions, COG functions, possible paralogues and orthologues, molecular weights, isoelectric points, operon structures, subcellular localization, signal peptides, transmembrane regions ...
an online tool for phylogenetic tree view (newick format) that allows multiple sequence alignments to be shown together with the trees (fasta format) EvolView [3] an online tool for visualizing, annotating and managing phylogenetic trees IcyTree [4] Client-side Javascript SVG viewer for annotated rooted trees. Also supports phylogenetic networks
Sequence alignments can be stored in a wide variety of text-based file formats, many of which were originally developed in conjunction with a specific alignment program or implementation. Most web-based tools allow a limited number of input and output formats, such as FASTA format and GenBank format and the
The UCSC site hosts a set of genome analysis tools, including a full-featured GUI interface for mining the information in the browser database, a FASTA format sequence alignment tool BLAT [9] that is also useful for simply finding sequences in the massive sequence (human genome = 3.23 billion bases [Gb]) of any of the featured genomes.