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A pill-splitter holding a tablet ready to split. Pill-splitting refers to the practice of splitting a tablet or pill to provide a lower dose of the active ingredient, or to obtain multiple smaller doses, either to reduce cost or because the pills available provide a larger dose than required.
[117] [107] [113] [114] Lipitor was on the market by 1996. [115] [118] By 2003, Lipitor had become the best selling pharmaceutical in the United States. [111] From 1996 to 2012, under the trade name Lipitor, atorvastatin became the world's best-selling medication of all time, with more than $125 billion in sales over approximately 14.5 years.
An early example of a pill comes from ancient Rome. They were made of zinc carbonates, hydrozincite and smithsonite. The pills were used for sore eyes and were found aboard a Roman ship that wrecked in 140 BC. However, these tablets were meant to be pressed on the eyes, not swallowed. [3] [4] Defects/imperfections arising during tablet ...
GO TIME. ENTER ANDY GALPIN, Ph.D., C.S.C.S. *D, a rock-star kinesiologist at California State University, Fullerton. Among his clients are some of the world’s most elite athletes, including NBA ...
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It isn't often that the two biggest of Big Pharma find themselves in a patent fight. Usually, it's a branded drugmaker fighting off a generics challenge from a copycat drugmaker. But this time it ...
Cholesterol synthesis appears to occur mostly at night, [140] so statins with short half-lives are usually taken at night to maximize their effect. Studies have shown greater LDL and total cholesterol reductions in the short-acting simvastatin taken at night rather than the morning, [141] [142] but have shown no difference in the long-acting ...
The effects of rosuvastatin on low-density lipoprotein (LDL) cholesterol are dose-related. Higher doses were more efficacious in improving the lipid profile of patients with hypercholesterolemia than milligram-equivalent doses of atorvastatin and milligram-equivalent or higher doses of simvastatin and pravastatin.
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