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Smoking exposes delicate cells inside the lungs directly to these compounds. This causes mutations in the DNA of the cells, which leads to cancer. According to the World Health Organization's report, "Tobacco Smoke and Involuntary Smoking", 80 percent of all cases of lung cancer are attributable to smoking.
Smoking most commonly leads to diseases affecting the heart and lungs and will commonly affect areas such as hands or feet. First signs of smoking-related health issues often show up as numbness in the extremities, with smoking being a major risk factor for heart attacks, chronic obstructive pulmonary disease (COPD), emphysema, and cancer, particularly lung cancer, cancers of the larynx and ...
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Among the 250 known harmful chemicals in tobacco smoke, at least 69 can cause cancer." [7] [2] [8] [9] See: Health effects of tobacco smoking and List of cigarette smoke carcinogens. Although many of these additives are used in making cigarettes, each cigarette does not contain all of these additives.
It is added to gum and hard lozenges used for nicotine replacement therapy in smoking cessation, such as in the Nicorette range of products. The use of the polymer as a delivery system maximizes the amount of nicotine released and absorbed by the oral mucosa . 80 to 90 percent of the nicotine released from the gum is absorbed by the mouth.
The health effects of tobacco had been debated by users, medical experts, and governments alike since its introduction to European culture. [1] Hard evidence for the ill effects of smoking became apparent with the results of several long-term studies conducted in the early to middle twentieth century, such as the epidemiology studies of Richard Doll and pathology studies of Oscar Auerbach.
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The consumption of tobacco products and its harmful effects affect both smokers and non-smokers, [9] and is a major risk factor for six of the eight leading causes of deaths in the world, including respiratory diseases, cardiovascular diseases, cerebrovascular diseases, periodontal diseases, teeth decay and loss, over 20 different types or subtypes of cancers, strokes, several debilitating ...