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  2. Opioid withdrawal - Wikipedia

    en.wikipedia.org/wiki/Opioid_withdrawal

    The expense of opioid replacement treatments in some countries has led some people to try treatments with limited evidence. At high doses, loperamide has been reported by some drug users to alleviate opioid withdrawal syndrome. [31] The doses reported in the literature are associated with a high risk of damage to the heart. [32]

  3. Common Anxiety Meds & How to Get Them From a Doctor - AOL

    www.aol.com/different-types-anxiety-meds-them...

    Medication for Anxiety: A Complete Guide. As you probably know from personal experience, anxiety can be a lot of things — a cause of insomnia, a roadblock to living your best life or a demon you ...

  4. Loperamide - Wikipedia

    en.wikipedia.org/wiki/Loperamide

    High doses of loperamide have been shown to cause a mild physical dependence during preclinical studies, specifically in mice, rats, and rhesus monkeys. Symptoms of mild opiate withdrawal were observed following abrupt discontinuation of long-term treatment of animals with loperamide. [44] [45]

  5. Peripherally selective drug - Wikipedia

    en.wikipedia.org/wiki/Peripherally_selective_drug

    For example, most opioids cause sedation when given at a sufficiently high dose, but peripherally selective opioids can act on the rest of the body without entering the brain and are less likely to cause sedation. [1] These peripherally selective opioids can be used as antidiarrheals, for instance loperamide (Imodium). [2]

  6. Single dose of LSD provides immediate and lasting relief from ...

    www.aol.com/news/single-dose-lsd-provides...

    One dose of LSD in a clinical trial significantly improved anxiety and lasted for 12 weeks, convincing the FDA to give the drug a breakthrough therapy designation.

  7. Which diabetes drugs are linked to the lowest depression risk?

    www.aol.com/diabetes-drugs-linked-lowest...

    One recent study found that GLP-1RAs may help lower the risk for depression compared to another medication for diabetes treatment, dipeptidyl peptidase-4 inhibitors. ... NFL sets 2025 salary cap ...

  8. Opioid - Wikipedia

    en.wikipedia.org/wiki/Opioid

    Tolerance is a physiologic process where the body adjusts to a medication that is frequently present, usually requiring higher doses of the same medication over time to achieve the same effect. It is a common occurrence in individuals taking high doses of opioids for extended periods, but does not predict any relationship to misuse or addiction.

  9. Just 100 micrograms of MM120 led to a 48% rate of remission from generalized anxiety disorder after 12 weeks, MindMed reported.

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