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It usually begins in the hands and feet and may progress to the arms and legs and sometimes to other parts of the body where it may affect the autonomic nervous system. It may be acute or chronic. A number of different disorders may cause polyneuropathy, including diabetes and some types of Guillain–Barré syndrome. [4] [5] [6]
For example, if the right foot is affected, the left foot is affected simultaneously or soon becomes affected. [1] In most cases, the legs are affected first, followed by the arms. The hands usually become involved when the symptoms reach above the ankle. [3] This is called a stocking-and-glove pattern of sensory disturbances. [4]
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
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"Wearing shoes that are too tight exacerbate neuropathy symptoms by compressing the nerves in the feet [and can] worsen pre-existing foot deformities, cause blisters, corns or calluses to develop ...
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Neuropathy has three sub-classifications; mononeuropathy is a result of an entrapped or traumatised nerve or nerve area, Mononeuropathy multiplex is linked to chronic diseases like leprosy, and polyneuropathy is an outcome of systemic, metabolic or toxic aetiology.
In this syndrome, decreased sensation and loss of reflexes occur first in the toes on each foot, then extend upward. It is usually described as a glove-stocking distribution of numbness, sensory loss, dysesthesia and nighttime pain. The pain can feel like burning, pricking sensation, achy or dull.
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