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The urea distribution volume , although traditionally thought of as 60% of body weight, may actually be closer to 50% of the body weight in women and 55% in men with stage V (GFR < 15 ml/min) chronic kidney disease. The clearance of urea during the dialysis session can be expressed in either or .
Urea allows the kidneys to create hyperosmotic urine (urine that has more ions in it - is "more concentrated" - than that same person's blood plasma). Preventing the loss of water in this manner is important if the person's body must save water in order to maintain a suitable blood pressure or (more likely) in order to maintain a suitable ...
Practical use of Kt/V requires adjustment for rebound of the urea concentration due to the multi-compartmental nature of the body. Kt/V may disadvantage women and smaller patients in terms of the amount of dialysis received. Normal kidney function may be modeled as optimal Glomerular filtration rate or GFR. GFR is usually normalized in people ...
For most patients, a GFR over 60 (mL/min)/(1.73 m 2) is adequate. But significant decline of the GFR from a previous test result can be an early indicator of kidney disease requiring medical intervention. The sooner kidney dysfunction is diagnosed and treated the greater odds of preserving remaining nephrons, and preventing the need for dialysis.
In nephrology, dialysis adequacy is the measurement of renal dialysis for the purpose of determining dialysis treatment regime and to better understand the pathophysiology of renal dialysis. [1] It is an area of considerable controversy in nephrology .
Kidney failure, also known as renal failure or end-stage renal disease (ESRD), is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. [2] Kidney failure is classified as either acute kidney failure, which develops rapidly and may resolve; and ...
A glomerular filtration rate (GFR) ≥ 60 mL/min/1.73 m 2 is considered normal without chronic kidney disease if there is no kidney damage present. Kidney damage is defined signs of damage seen in blood, urine, or imaging studies which includes lab albumin/creatinine ratio (ACR) ≥ 30. [59]
For most patients, a GFR over 60 mL/min/1.73 m 2 is adequate. But significant decline of the GFR from a previous test result can be an early indicator of kidney disease requiring medical intervention. The sooner kidney dysfunction is diagnosed and treated the greater odds of preserving remaining nephrons, and preventing the need for dialysis.
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