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A new study finds even people over age 75 can get heart benefits from statins. Previously most clinical trials evaluating statins have not included people in this age group.
Use during pregnancy may harm the baby. [6] Like all statins, rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing cholesterol. [6] Rosuvastatin was patented in 1991 and approved for medical use in the United States in 2003. [6] [7] It is available as a generic medication. [6]
Researchers tested simvastatin, later sold by Merck as Zocor, on 4,444 patients with high cholesterol and heart disease. After five years, the study concluded the patients saw a 35% reduction in their cholesterol, and their chances of dying of a heart attack were reduced by 42%. [12] [192] In 1995, Zocor and Mevacor both made Merck over US$1 ...
The study authors reported that for people younger than 60, 65% of women and 79% of men received cholesterol-lowering medication after diagnosis. Three years later, 52% of women and 78% of men ...
Part of the power of statins lies in the fact that they cause few side effects. “Generally, about 90 out of 100 people have no trouble with a stain,” says Dr. Blumenthal. These Are the Statin ...
A risk exists of muscle damage (myopathy and rhabdomyolysis) with statins. Hypercholesterolemia is not a risk factor for mortality in persons older than 70 years and risks from statin drugs are more increased after age 85. [2] Fibrates are indicated for hypertriglyceridemia. Fibrates typically lower triglycerides by 20% to 50%.
Use during pregnancy may harm the baby and use during breastfeeding is not recommended. [3] It works by decreasing the liver's ability to produce cholesterol by blocking the enzyme HMG-CoA reductase. [2] Lovastatin was patented in 1979 and approved for medical use in 1987. [4] It is on the World Health Organization's List of Essential Medicines ...
An alternative to statins may help reduce deaths from heart disease among people with high levels of LDL, or “bad” cholesterol, new research finds.. When taken as a daily pill, bempedoic acid ...