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Beyond adverse effects from the herb itself, "adulteration, inappropriate formulation, or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life threatening or lethal." [3]
A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs. Interactions may occur by simultaneous targeting of receptors, directly or indirectly. For example, both Zolpidem and alcohol affect GABA A receptors, and their simultaneous consumption results in the overstimulation of the receptor, which can ...
Secondary metabolites and pigments may have therapeutic actions in humans, and can be refined to produce drugs; examples are quinine from the cinchona, morphine and codeine from the poppy, and digoxin from the foxglove. [1] In Europe, apothecaries stocked herbal ingredients as traditional medicines.
Best known examples of adverse herb‑drug interactions are grapefruit or St John's wort, contraindicated for several medications including Paxlovid and oral contraceptives, but other herbs also affect the CYP enzyme family, showing herb‑drug interactions. [37] [38] [39]
Drugs that interact usually share three common features: they are taken orally, normally only a small amount enters systemic blood circulation, and they are metabolized by CYP3A4. [1] The effects on the CYP3A4 in the liver could, in principle, cause interactions with non-oral drugs, [citation needed] and non-CYP3A4-mediated effects also exist. [31]
You’re wise to be wondering about minoxidil drug interactions. Both over-the-counter (OTC) and prescription medications have the potential to interact with other substances, including supplements.
Herbs were also commonly used in the traditional medicine of ancient India, where the principal treatment for diseases was diet. [13] De Materia Medica, originally written in Greek by Pedanius Dioscorides (c. 40 – c. 90 CE) of Anazarbus, Cilicia, a physician and botanist, is one example of herbal writing used over centuries until the 1600s. [14]
This page is a sortable table of plants used as herbs and/or spices.This includes plants used as seasoning agents in foods or beverages (including teas), plants used for herbal medicine, and plants used as incense or similar ingested or partially ingested ritual components.