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Levofloxacin Trovafloxacin. Fluoroquinolones are often used for genitourinary infections [5] and are widely used in the treatment of hospital-acquired infections associated with urinary catheters. In community-acquired infections, they are recommended only when risk factors for multidrug resistance are present or after other antibiotic regimens ...
Like all fluoroquinolones, levofloxacin is a fluorinated quinolone carboxylic acid. It is a chiral molecule and the pure (−)-(S)-enantiomer of the racemic drug ofloxacin. [57] [58] [59] This enantiomer binds more effectively to the DNA gyrase enzyme and to topoisomerase IV than its (+)-(R)-counterpart. [54]
Among the fluoroquinolones, ciprofloxacin and levofloxacin are used more frequently for the treatment of UTIs. These agents are well-absorbed orally and achieve significant concentrations in urine and various tissues. [12] However, fluoroquinolones administration carries risk of GI symptoms, confusion, hypersensitivity, tendinopathy, and ...
Levofloxacin, which is marketed under the brand name Levaquin in the U.S. and Tavanic in the EU, is often prescribed for pneumonia, urinary tract infections and infections of the abdomen.
Quinolones/Fluoroquinolones Ciprofloxacin: Cipro, Ciproxin, Ciprobay: Urinary tract infections, bacterial prostatitis, community-acquired pneumonia, bacterial diarrhea, mycoplasmal infections, gonorrhea: Nausea (rare), irreversible damage to central nervous system (uncommon), tendinosis (rare)
Category: Fluoroquinolone antibiotics. ... Levofloxacin; Lomefloxacin; M. ... This page was last edited on 5 April 2024, at 21:10 (UTC).
On July 8, 2008, the FDA ordered a boxed warning on certain antibiotic medications containing fluoroquinolone, which has been linked to tendon ruptures and tendinitis. Included were the popular drugs Cipro (ciprofloxacin), Levaquin (levofloxacin), Avelox (moxifloxacin), Noroxin (norfloxacin) and Floxin . [19]
One of the most prominent changes is the cost-of-living adjustment (COLA), which will be 2.5% this year and is slated to boost the average retiree's checks by just under $50 per month.
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