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Crohn's disease is an inflammatory bowel disease that causes chronic inflammation of the GI tract, which extends from your stomach all the way down to your anus. Different areas of the GI tract can be affected in different people, and it often spreads into the deeper layers of the bowel.
There is currently no cure for Crohn's disease, and there is no single treatment that works for everyone. One goal of medical treatment is to reduce the inflammation that triggers your signs and symptoms. Another goal is to improve long-term prognosis by limiting complications.
Each year, Mayo Clinic doctors diagnose and treat nearly 6,000 adults and children with Crohn's disease. Mayo specializes in helping people with severe symptoms that haven't responded well to treatment in the past.
Crohn's disease is an inflammatory bowel disease that causes chronic inflammation of the GI tract, which extends from your stomach all the way down to your anus. Different areas of the GI tract can be affected in different people, and it often spreads into the deeper layers of the bowel.
Doctors at Mayo Clinic are also actively exploring new biological therapies to help manage Crohn's disease. Some investigators are studying possible links between diet, the immune system and bacteria in the digestive tract (microbiome).
Advances in the treatment of Crohn's disease and ulcerative colitis. When used in a treat-to-target approach, therapies for mucosal healing may favorably modify the natural history of inflammatory bowel disease (IBD), reducing the need for steroids and risk of hospitalization.
The inflammation caused by Crohn's disease often spreads deep into the layers of affected bowel tissue. Crohn's disease can be both painful and debilitating, and sometimes may lead to life-threatening complications.
Crohn's disease most commonly affects the small intestine. However, it can also affect the large intestine and uncommonly, the upper gastrointestinal tract. Both ulcerative colitis and Crohn's disease usually are characterized by diarrhea, rectal bleeding, abdominal pain, fatigue and weight loss.
Surgery for Crohn's disease. Up to two-thirds of people with Crohn's disease will require at least one surgery in their lifetime. However, surgery does not cure Crohn's disease.
The Inflammatory Bowel Disease Clinic is devoted to diagnosing and treating inflammatory bowel diseases, including ulcerative colitis, Crohn's disease and pouchitis. This clinic also provides diagnosis and treatment for patients with microscopic colitis, lymphocytic colitis and collagenous colitis.