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Molecular diagnostics. Molecular diagnostics is a collection of techniques used to analyze biological markers in the genome and proteome, and how their cells express their genes as proteins, applying molecular biology to medical testing. In medicine the technique is used to diagnose and monitor disease, detect risk, and decide which therapies ...
Medical diagnosis (abbreviated Dx, [ 1 ]Dx, or Ds) is the process of determining which disease or condition explains a person's symptoms and signs. It is most often referred to as a diagnosis with the medical context being implicit. The information required for a diagnosis is typically collected from a history and physical examination of the ...
In medical diagnosis, test sensitivity is the ability of a test to correctly identify those with the disease (true positive rate), whereas test specificity is the ability of the test to correctly identify those without the disease (true negative rate). If 100 patients known to have a disease were tested, and 43 test positive, then the test has ...
Immunoassay. An immunoassay (IA) is a biochemical test that measures the presence or concentration of a macromolecule or a small molecule in a solution through the use of an antibody (usually) or an antigen (sometimes). The molecule detected by the immunoassay is often referred to as an " analyte " and is in many cases a protein, although it ...
Diagnostic microbiology is the study of microbial identification. Since the discovery of the germ theory of disease, scientists have been finding ways to harvest specific organisms. Using methods such as differential media or genome sequencing, physicians and scientists can observe novel functions in organisms for more effective and accurate ...
Biomarker (medicine) In medicine, a biomarker is a measurable indicator of the severity or presence of some disease state. It may be defined as a "cellular, biochemical or molecular alteration in cells, tissues or fluids that can be measured and evaluated to indicate normal biological processes, pathogenic processes, or pharmacological ...
Presumptive and confirmatory tests. Presumptive tests, in medical and forensic science, analyze a sample and establish one of the following: The sample is definitely not a certain substance. The sample probably is the substance. For example, the Kastle–Meyer test will show either that a sample is not blood or that the sample is probably blood ...
Serology is the scientific study of serum and other body fluids.In practice, the term usually refers to the diagnostic identification of antibodies in the serum. [1] Such antibodies are typically formed in response to an infection (against a given microorganism), [2] against other foreign proteins (in response, for example, to a mismatched blood transfusion), or to one's own proteins (in ...