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The procedure is to take the child's weight in pounds, divide by 150 lb, and multiply the fractional result by the adult dose to find the equivalent child dosage.For example, if an adult dose of medication calls for 30 mg and the child weighs 30 lb, divide the weight by 150 (30/150) to obtain 1/5 and multiply 1/5 times 30 mg to get 6 mg.
Children ≥6 years & adults NDRI: Approved: Highly efficacious, [124] therapeutic effects are usually seen within 0.5–1.5 hours of oral administration (depending on formulation). No significant advantages over methylphenidate at equipotent dosages. Non-classical Atomoxetine: Strattera [136] Children ≥6 years & adults Children ≥6 years ...
Adderall and Mydayis [11] are trade names [note 2] for a combination drug containing four salts of amphetamine.The mixture is composed of equal parts racemic amphetamine and dextroamphetamine, which produces a (3:1) ratio between dextroamphetamine and levoamphetamine, the two enantiomers of amphetamine. [13]
Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1] Tables of this general type are also available for NSAIDs , benzodiazepines , depressants , stimulants , anticholinergics and others.
Addiction is a serious risk with heavy recreational amphetamine use, but is unlikely to occur from long-term medical use at therapeutic doses; [123] [124] [65] in fact, lifetime stimulant therapy for ADHD that begins during childhood reduces the risk of developing substance use disorders as an adult. [41]
The dosage may vary and is titrated to effect, with some guidelines recommending initial treatment with a low dose. [31] Methylphenidate is available in both immediate-release and extended-release (XR) formulations to provide a sustained release of the drug. [32] [33] Methylphenidate is not approved for children under six years of age. [34] [35]
Amphetamine [note 2] (contracted from alpha-methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity; it is also used to treat binge eating disorder in the form of its inactive prodrug lisdexamfetamine.
Different ATS also have different toxic dose. Methamphetamine fatality from ATS have been reported after ingestion of a minimal dose of 1.3 mg/kg, while the estimated minimum lethal dose in a non-addicted adult is 200 mg. [14] [26] Generally, children are more likely to develop toxicity and have lower chances of developing tolerance. [14]