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Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution, although only in a few cases are genes the primary cause of obesity.
16p11.2 deletion syndrome is a rare genetic condition caused by microdeletion on the short arm of chromosome 16. Most affected individuals experience global developmental delay and intellectual disability, as well as childhood-onset obesity. [1] 16p11.2 deletion is estimated to account for approximately 1% of autism spectrum disorder cases. [3] [4]
Genome: The Autobiography of a Species in 23 Chapters is a 1999 popular science book by the science writer Matt Ridley, published by Fourth Estate.The chapters are numbered for the pairs of human chromosomes, one pair being the X and Y sex chromosomes, so the numbering goes up to 22 with Chapter X and Y couched between Chapters 7 and 8.
Obesity has been associated with an inflammatory state, which is chronic and low-grade inflammation, known as meta-inflammation. [ 6 ] [ 7 ] Meta-inflammation is subclinical meaning that while there is an increase in circulating pro-inflammatory factors, no clinical signs of inflammation , heat, pain, and redness, are seen with meta ...
The Journey of Man: A Genetic Odyssey is a 2002 book by Spencer Wells, an American geneticist and anthropologist, in which he uses techniques and theories of genetics and evolutionary biology to trace the geographical dispersal of early human migrations out of Africa. The book was made into a TV documentary in 2003.
Years from now, we will look back in horror at the counterproductive ways we addressed the obesity epidemic and the barbaric ways we treated fat people—long after we knew there was a better path. I have never written a story where so many of my sources cried during interviews, where they shook with anger describing their interactions with ...
Who We Are and How We Got Here is a 2018 book on the contribution of genome-wide ancient DNA research to human population genetics by the geneticist David Reich.He describes discoveries made by his group and others, based on analysis and comparison of ancient and modern DNA from human populations around the world.
While obesity is an independent risk factor for type 2 diabetes that may be linked to lifestyle, obesity is also a trait that may be strongly inherited. [21] [22] Other research also shows that type 2 diabetes can cause obesity as an effect of the changes in metabolism and other deranged cell behavior attendant on insulin resistance. [23]