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Physical illnesses, including hypothyroidism and mitochondrial disease, can also trigger depressive symptoms. [4] [5] Neural circuits implicated in depression include those involved in the generation and regulation of emotion, as well as in reward. Abnormalities are commonly found in the lateral prefrontal cortex whose putative function is ...
There are many psychiatric and medical conditions that may mimic some or all of the symptoms of depression or may occur comorbid to it. [11] [12] [13] A disorder either psychiatric or medical that shares symptoms and characteristics of another disorder, and may be the true cause of the presenting symptoms is known as a differential diagnosis. [14]
Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to ...
The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), is the 2013 update to the Diagnostic and Statistical Manual of Mental Disorders, the taxonomic and diagnostic tool published by the American Psychiatric Association (APA).
Neuropharmacology is the study of how drugs affect function in the nervous system, and the neural mechanisms through which they influence behavior. [1] There are two main branches of neuropharmacology: behavioral and molecular.
Neurochemistry is the study of the different types, structures, and functions of neurons and their chemical components. Chemical signaling between neurons is mediated by neurotransmitters, neuropeptides, hormones, neuromodulators, and many other types of signaling molecules.
The neurotrophic hypothesis of depression [1] proposes that major depressive disorder (MDD) is caused, at least partly, by impaired neurotrophic support.Neurotrophic factors (also known as neurotrophins) are a family of closely related proteins which regulate the survival, development, and function of neurons in both the central and peripheral nervous systems.
The impact of this weak imbalance in neurochemistry can be seen in the consistent features of behaviour in healthy people (temperament). In this sense temperament (as neuro-chemically-based individual differences) and mental illness represents varying degrees along the same continuum of neurotransmitter imbalance in neurophysiological systems ...