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Betahistine was once believed to have some positive effects in the treatment of Ménière's disease and vertigo, [3] but more recent evidence casts doubt on its efficacy. [4] [5] Studies of the use of betahistine have shown a reduction in symptoms of vertigo and, to a lesser extent, tinnitus, but conclusive evidence is lacking at present.
An H 3 receptor antagonist is a type of antihistaminic drug used to block the action of histamine at H 3 receptors.. Unlike the H 1 and H 2 receptors which have primarily peripheral actions, but cause sedation if they are blocked in the brain, H 3 receptors are primarily found in the brain and are inhibitory autoreceptors located on histaminergic nerve terminals, which modulate the release of ...
A histamine agonist is a drug which causes increased activity at one or more of the four histamine receptor subtypes.. H 1 agonists promote wakefulness. [1]H 2: Betazole and Impromidine are examples of agonists used in diagnostics to increase histamine.
Betahistine at high doses (such as 144 mg/day) can yield similar vertigo control as intratympanic dexamethasone. [16] [17] Antivirals have been proven effective for those who suspect a viral cause for their cochlear Hydrops. [18] For some, surgery may be effective, such as an endolymphatic sac decompression. Surgery is often reserved for cases ...
As of 2014, betahistine is often used as it is inexpensive and safe; [5] but evidence does not justify its use in Ménière's disease. [ 36 ] [ 37 ] However, recent pharmacokinetic experiments have shown that combination therapy with Monoamine oxidase inhibitors can drastically increase the bioavailability of betahistine in humans, [ 38 ] and ...
Cinnarizine is predominantly used to treat nausea and vomiting associated with motion sickness, [6] vertigo, [8] Ménière's disease, [9] or Cogan's syndrome. [3] It is one of only a few drugs that has a beneficial effect in the chronic treatment of the vertigo and tinnitus associated with Ménière's disease.
The DizzyFIX is a home medical device designed to assist in the treatment of benign paroxysmal positional vertigo (BPPV) and its associated vertigo. [1] The device is a head-worn representation of semi-circular canals. The device is filled with fluid and a particle representing the otoconia (loose hard particles) associated with BPPV.
This is followed by gently bringing the head back to the starting position. The examiner then quickly rotates the head 90° to the right side and checks again for vertigo and nystagmus. [24] In this roll test, the person may experience vertigo and nystagmus on both sides, but rotating toward the affected side will trigger a more intense vertigo.