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Giovannucci is known for his research into the health benefits of obtaining vitamin D through sunlight exposure. [4] [5] He has said that for every death caused by skin cancer resulting from sun exposure, 30 deaths might be prevented due to increased vitamin D intake, [4] and that "It does seem that Vitamin D levels seem to be a real predictor of heart disease."
Taking vitamin D supplements has no significant effect on cancer risk. [98] Vitamin D 3, however, appears to decrease the risk of death from cancer but concerns with the quality of the data exist. [99] Nevertheless, studies suggest that Vitamin D deficiency is associated with increased risk of development melanoma. [100]
Michael F. Holick (/ ˈ h ɒ l ɪ k / HOLL-ik; [1] born 1946) is an American adult endocrinologist, specializing in vitamin D, such as the identification of both calcidiol, the major circulating form of vitamin D, and calcitriol, the active form of vitamin D. His work has been the basis for diagnostic tests and therapies for vitamin D-related ...
The study, which was published in the journal Alzheimer’s & Dementia Diagnosis, Assessment, & Disease Monitoring in 2023, analyzed the impact of vitamin D on the development of dementia in ...
Also a 2008 study published in Cancer Research has shown the addition of vitamin D 3 (along with calcium) to the diet of some mice fed a regimen similar in nutritional content to a new Western diet with 1000 IU cholecalciferol per day prevented colon cancer development. [33]
Norman's research was in the area of cellular and molecular endocrinology, where he was internationally known for his breakthroughs in the study of vitamin D. [2] This included the mechanisms of action of the steroid hormone 1,25-dihydroxycholecalciferol, vitamin D structure-function relationships, and actions of the vitamin D receptor (VDR).
Vitamin D and Omega-3 Trial (VITAL) [1] was a clinical trial designed to investigate the use of daily dietary supplements of vitamin D and fish oil.. The sponsor of the study was Brigham and Women's Hospital, collaborating with The National Cancer Institute, National Heart, Lung, and Blood Institute, Office of Dietary Supplements, National Institute of Neurological Disorders and Stroke ...
1α-Hydroxyvitamin D 5 is a chemical derivative of vitamin D 5.The motive to study 1α-hydroxyvitamin D 5 as a potential pharmaceutical drug stemmed from the tendency of calcitriol, a natural metabolite produced in the kidney, to cause toxic hypercalcemia in patients when dosed at concentrations needed to interrupt prostate cancer cells' cycle and stimulate apoptosis.