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PSGAG is first administered as a series of injections over several weeks, and can be continued once or twice a month thereafter. [10] It is normally injected intramuscularly, though can also be injected intra-articularily (directly into the joint) in horses or subcutaneously in off-label uses. [2]
While it is a prescription or over-the-counter drug in 22 countries, chondroitin is regulated in the U.S. as a dietary supplement [36] by the Food and Drug Administration. In Europe, chondroitin sulfate formulations are approved as drugs with evidenced efficacy and safety demonstrated by clinical trials in people with osteoarthritis. [37]
Another study examined both the serum and the joint synovial fluid after nasogastric (oral) or intravenous administration of 20 mg/kg glucosamine hydrochloride to eight adult horses. [48] Although joint fluid concentrations of glucosamine reached 9–15 μmol/L following intravenous dosing, it was only 0.3–0.7 μmol/L with nasogastric dosing.
Joint supplements come in various forms, like powders mixed with liquid, capsules, tablets, or even liquids. Tablets or capsules may be more convenient but difficult to swallow, while powders mix ...
Pros: All-natural. Gluten-free. Contains BioPerine to improve nutrient absorption. Cons: Only includes turmeric for joints. Naguna Labs Turmeric Curcumin contains BioPerine, a patented piperine ...
Dr. Michael Roizen is 78 but says his biological age is 57.6. He takes five supplements daily, including a multivitamin.
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