Search results
Results from the WOW.Com Content Network
It is a type of organelle made up of two subunits – rough endoplasmic reticulum (RER), and smooth endoplasmic reticulum (SER). The endoplasmic reticulum is found in most eukaryotic cells and forms an interconnected network of flattened, membrane-enclosed sacs known as cisternae (in the RER), and tubular structures in the SER.
Synthesis of proteins is by the rough endoplasmic reticulum (RER), and both the rough and smooth endoplasmic reticulum (SER) are involved in secretion of the proteins formed. [citation needed] The endoplasmic reticulum (ER) is involved in conjugation of proteins to lipid and carbohydrate moieties synthesized by, or modified within, the hepatocytes.
The study found significant differences between human liver microsomes and human liver S9 fractions in drug-metabolizing enzyme and transporter protein concentrations. The protein-protein correlations of these drug-metabolizing enzymes and transporters was determined relating to the two hepatic preparations.
Ser or S phosphorylation, O-linked glycosylation, N-acetylation (N-terminus) Threonine: Thr or T phosphorylation, O-linked glycosylation, N-acetylation (N-terminus) Tryptophan: Trp or W mono- or di-oxidation, formation of kynurenine, tryptophan tryptophylquinone: Tyrosine: Tyr or Y sulfation, phosphorylation Valine: Val or V N-acetylation (N ...
The ERGIC lies between the rough endoplasmic reticulum (RER) and Golgi on the secretory pathway. The endoplasmic-reticulum–Golgi intermediate compartment (ERGIC) is an organelle in eukaryotic cells. This compartment mediates transport between the endoplasmic reticulum (ER) and Golgi complex, facilitating the sorting of cargo. [1]
A C-C bond is formed between the first carbon of the alpha-mannose and the second carbon of the tryptophan. [13] However, not all the sequences that have this pattern are mannosylated. It has been established that, in fact, only two thirds are and that there is a clear preference for the second amino acid to be one of the polar ones (Ser, Ala ...
The unfolded protein response (UPR) is a cellular stress response related to the endoplasmic reticulum (ER) stress. [1] It has been found to be conserved between mammalian species, [2] as well as yeast [1] [3] and worm organisms.
Under the portion of Rough Endoplasmic Reticulum section there were bullet point that were provided to understand the multiple key functions of the RER; however, the terms were much more higher level then they needed to be omitting clathrin, SNAP, and SNARE which are all terms that are unfamiliar will make this article more understanding.